Many organized tours run out of La Paz or towns closest to the attractions you're likely to wish to visit. Tours are a convenient way to visit a site when you are short of time or motivation, and are frequently the easiest way to visit remote areas. They can also be relatively cheap, depending on the number of people in your group and the mode of transport.
There are scores of companies offering trekking, mountain-climbing and rainforest-adventure packages around Bolivia. For climbing in the Cordilleras, operators offer customized expeditions and can arrange anything from guide and transportation to equipment, porters and a cook. Some also rent trekking equipment.
It’s best to check an agency's website first, before making contact and bookings.