Bus Queensland has a daily service from Mt Isa to Brisbane ($175, 22 hours) via Charleville and Longreach, and travels three times a week to Townsville ($99, 12 hours) via Charters Towers.
Mount Isa Coaches offers a shuttle service between the airport and most CBD hotels. The service meets (and arranges city departures appropriate for) all commercial flights.
Offers twice-weekly services to Townsville ($99, 11½ hours). The depot is at Outback at Isa.
Rex flies daily between Mt Isa and Townsville and services many outback destinations, including Birdsville and Burketown.
The Inlander train runs between Mt Isa and Townsville ($108, 21 hours) twice a week.
Avis also has an office at the airport.
Car rental desk at the airport.
Also pick-up at the airport.
Local taxi service. There's a taxi rank outside Kmart.
Qantas flies to Brisbane and Townsville from Mt Isa.