Fishing enthusiasts needn't be deterred by the high altitude. Río El Tigre, at 2600m, offers year-round trout fishing with the snowcapped Andean peaks in the near distance. There's also horseback riding and hiking in the nearby precordilleras. Ski and climbing shops rent equipment for those heading to Los Penitentes and Parque Provincial Aconcagua respectively.
In general, Uspallata's accommodations are of fairly low standards, but regardless, in the summer high season (when climbers from around the world descend on the area), reservations are wise. And it's still the most logical place to overnight for those day-tripping to Parque Provincial Aconcagua and surrounding sights or to merely experience the scenery along RN 7.
This is a crossroads town, and as such, the few restaurants on hand are geared to itinerant groups and aren't liable to inspire repeat visits. And apart from the two mediocre parrillas near one another just south of the intersection, there isn't much to speak of in terms of full service sit down restaurants.