Once owned by Argentine icon, General Pueyrredón, the Museo Pueyrredón is an old colonial villa set on spacious grounds with faraway views of the Río de la Plata. Note the algarrobo (carob tree) under which Pueyrredón and San Martín planned strategies against the Spanish. To get here from the cathedral, follow Av Libertador south five blocks, turn left on Peña and after two blocks turn right onto Rivera Indarte.
Even more glamorous is the Unesco site Villa Ocampo, a wonderfully restored mansion. Victoria Ocampo was a writer, publisher and intellectual who dallied with the literary likes of Borges, Cortázar, Sabato and Camus. The gardens are lovely here; guided tours are offered in English and Spanish.
Also worth a visit is Quinta Los Ombúes, a historical house with some period items once owned by prominent local figures. It’s located one block behind the cathedral.