Four Tourist Travel runs an airport shuttle for AR$130 per person that meets most flights; from town, it needs to be booked in advance. A remise costs AR$350 to or AR$450 from the airport, which is 25km from town.
Frequent buses cross to Foz do Iguaçu, Brazil (AR$25 or R$5, 40 minutes, every 20 minutes 6:30am to 7:30pm), and to Ciudad del Este, Paraguay (AR$40, one hour, hourly 6:50am to 5:45pm), from the local side of the bus terminal. There are also buses direct to the Brazilian side of the Iguazú Falls (AR$80 return, hourly 8:30am to 2:30pm, last return 5pm), which are inexplicably much cheaper than the bus to the local park.
A taxi to Foz costs around AR$450; to the Brazilian side of the Iguazú Falls it’s AR$600 return. Avoid the remise office at the bus terminal: it's more expensive than others. Always negotiate. We particularly like the taxi stop on Córdoba opposite El Mensú, which has some knowledgeable multilingual drivers and metered cabs.
Ostensibly air-conditioned local buses cost AR$15 and are useful for reaching hotels and attractions located along the falls road, or the triple frontier marker.
Another option is the hop-on, hop-off double-decker Bus Turistica although service is fairly infrequent, which means long stops at the attractions it visits.
Run by the local government, Eco Bicis offers free bicycle rental near the plaza. For a more solid ride Jungle Bike offers bikes for hire, as well as guided excursions to rarely visited local nature reserves. Mountain bikes are available for AR$350–AR$400 per day.