Cono Sur Three buses run daily at 5am, 10am and 4pm to Neuquén (AR$632, six hours) via Zapala (AR$376, three hours). If you’re headed for Chos Malal, take one of the two morning buses and change in Las Lajas (AR$276, 2½ hours).
In summer (December through February) several daily buses run to and from Copahue.
Car & Motorcycle
If driving to Chos Malal, you'll have to take the unsealed, wonderfully scenic RP 21 – the road less travelled. After emerging on RN 21, take the RN 6 rather than the RN 4.