Getting There & Away
Cafayate is at the center of most northwest Argentina road-trip itineraries as it's easily reached from Salta through the twisted, colorful and almost psychedelic rockscapes of the Quebrada de Cafayate, or via the equally spectacular and mostly unpaved RN 40, which snakes through the Valles Calchaquíes.
For those without wheels, the new bus terminal is at the northern entrance to town, where you can connect to Salta (AR$215, four hours, five to six daily) and Angastaco (AR$81, two hours) via San Carlos (AR$23, 45 minutes, one to four daily). Buses also leave two to four times daily for Tucumán (AR$385 to AR$430, five to 6½ hours) via Amaicha and Tafí del Valle (AR$230 to AR$275, 2½ to four hours); others go via Santa María (AR$120, two hours). Counterintuitively, quicker buses can be cheaper.