Tampa International Airport is the region's third busiest hub. It's located 8 miles west of downtown, off Hwy 589.
HART bus 30 ($2, 25 minutes, every 30 minutes) picks up and drops off at the Red Arrival Desk on the lower level of the airport; exact change is required.
All major car agencies have desks at the airport. By car, take the I-275 to N Ashley Dr, turn right and you're in downtown.