1

Do you have to go in that direction? Patagonian winds are very tough if you're going south-north.

Also, at times the Western route is much faster, but it can also be boring. You'll want to be spending time to the east of the Andes too.

2

I would definitely do the western side. Start at Ushuaia, then criss cross your way between Chile and Argentina up the continent. Punta Arena is a nice break but not much to see. Then head up to Natales and drop your bike there and enjoy a few days of fantastic trekking at the world famous Torres Del Paine. Then make your way through the dreaded Route 40, a desolate waste land of a road with wind speed of up to 100KM/H or at least that was what it felt like for me. This road is a necessary evil for access to El Calafate for the amazing Perito Moreno. Then up a little further at El Chalten, there is Fitz Roy and Cerro Torres. From here I cross back to Chile at Lago General Carrera. Not much to see on this section other than pain and suffering on Route 40. I suggest you cross back into Chile and enjoy Carretera Austral from the one end to the other. But I suspect this ride could be even tougher than the Argentina side. Riding in Carretera Austral is like riding in a National Park. Every corner something amazing awaits you. Eventually, you will end up in Chaiten. The road more or less ends here. You can go further north, but then it gets quite complicated. Take the boat to Castro and keep going north. Just make sure you don't take the Pan-Americana to Santiago. That road will put you to sleep, nothing to see at all. I have not been to the north of Santiago. A great way to enter Bolivia is from Atacama through Salar Uyuni to Uyuni the town. If you are not going absolute straight line, there are quite a few thing you shouldn't miss such as the fantastic lifestyle of Buenos Aires, Iguazu Falls, The Pantanals, etc...........