The official currency is the Syrian pound (S£), also called the lira. There are 100 piastres (also known as qirsh) to a pound but this is redundant as the smallest coin is one pound. Other coins come in denominations of two, five, 10 and 25. Notes come in denominations of 50, 100, 200, 500 and 1000.
There’s at least one branch of the Commercial Bank of Syria in every major town and most will change US dollars or euros. There’s also a small number of officially sanctioned private exchange offices, which change cash at official bank rates. The advantage is that whereas banks usually close for the day at 12.30pm or 2pm, the exchange offices are often open until 7pm.