Chiesa di San Domenico
Flanked by cafes, the elegant Piazza del Plebiscito has been Ancona's meeting spot since medieval times. It's dominated by this baroque church, containing the superb Crucifixion by Titian and Annunciation by Guercino. That gigantic statue in front is Pope Clement XII, who was honoured by the town for giving it free port status. The nearby fountain is from the 19th century.