The best price found from United States to Santorini is on May 1st, 2017, travelling with British Airways. See more options, compare prices and book: search flights.
Santorini Airport has flights year-round to/from Athens (from €64, 45 minutes) with Olympic Air (www.olympicair.com) and Aegean Airlines (www.aegeanair.com). Seasonal European connections are plentiful, including easyJet from London, Rome and Milan.
There are frequent bus connections between Fira’s bus station and the airport, located southwest of Monolithos Beach. The first leaves Fira around 7am and the last 9pm (€1.60, 20 minutes). Most accommodation providers will arrange (paid) transfers.