Fantastic All Around
I have a Crumpler shoulder bag for regular use of my photographic equipment and I didn't want to get a mainstream (Lowepro/Tamrac etc.) backpack since they attract attention. I was about to purchase a regular Northface backpack and [cre-ate ]my own camera pack with inserts when I came across this bag on the internet and decided to give it a try. It was exactly what I was looking for!! First and foremost, I was very impressed with the quality and look of the bag. The pack is large and a bit heavy when empty, BUT essential for carrying and protecting a Nikon D700 w/ a 24-70 & 70-200 pro lens, flash and video camera while skiing. The removable camera block is a great feature if you take your camera to a restaurant or just walk around (apres skiing). Like I said, the bag is large and not a stylish accessory to lug into a nice restaurant or shop. Once the block is removed, the pack can also hold a tremendous amount of gear in the main compartment. The back of the pack has a firm and padded zip down opening that provides a good solid/comfortable feel across the back. VERY IMPORTANT for a long day of skiing!! One fantastic feature I loved: The bag seems to have an endless amount of straps and buckles all over (which itself is a fantastic feature). When you take the elastic band off each strap that came with the packaging (elastic band holds the extra length of the strap after the buckle), there are straps dangling off every inch of the pack and it looks like a huge/cluttered mess. **Here's the kicker** Almost every strap on the pack comes with a built in elastic band allowing you to tightly store the excess length of the strap once adjusted...maintaining a very clean and high quality look and feel to the bag. This is a must have camera bag for medium to large SLR camera's!!

Great Quality
The bag is exactly what I was looking for. It is replacing my current Canon backpack. The Dakine backpack is much larger and offers much more protection to the gear inside of it. I also like the removable block which will be perfect when I have my kid and his stroller with me.

Nice for the amateur, falls short for the pros
With a large capacity (33L according to DaKine; 29L according to Altrec), I figured this pack would be big enough to hold a variety of photo gear, as well as the 10 essentials to accompany me in the backcountry, but it fails to accommodate pro-sized bodies like the Canon 1D series or amateur bodies with the vertical grip attached. In addition to not being able to fit my camera bodies in the pack, its design carries a bulky feeling with their pack inside of a pack design. Having a bag within a bag severely decreases the cargo room for gear like food, water, extra clothing or survival gear while out hiking or riding. In this pack, it's all but impossible to store anything else. You can cram in a 15" laptop in the front compartment, but then your cargo room is taken up. While this pack is not right for me as a professional photographer, it would probably suit the weekend warrior just fine. It looks stylish, can hold a tripod externally, but does not have the deployable water compartment as advertised. Just a couple of tight side pockets. Load levelers, chest strap and generously padded waist strap make it a comfortable fit, but the lack of the ability to carry cameras with the vertical grip makes it a deal-breaker. I'll be returning it for something else. In the photo world, there's a fine line between comfort, cargo, and padding and with the bulky interior design of the Sequence, this pack's ability to fill the 29L capacity efficiently falls short for me.